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About Arda

Traditional pharmaceuticals modulate individual proteins and signaling pathways, aiming to nudge tissues and organs back toward health. But cells - not proteins - are the functional units of diseased tissue, and their behavior is governed by redundant networks that single-target drugs struggle to change. Arda Therapeutics offers a groundbreaking alternative: we target cells, not pathways. By depleting specific pathogenic cells that drive chronic diseases such as fibrosis and inflammation, we shut down the entire network of dysfunction at once, rather than blocking one of many redundant nodes.

What makes this possible is an explosion of single-cell data. Arda's discovery engine integrates multi-modal single-cell, spatial, and genetic data to pinpoint pathogenic cell states and the surface markers that distinguish them from healthy cells with unprecedented precision. We engineer targeted biologics that eliminate only the harmful cells, sparing healthy tissue and opening the door to greater efficacy and episodic treatment. Backed by leading life-science and technology investors - and built by a team that blends computational biology, drug development, and cell-depletion expertise - Arda is defining a new domain of medicine for inflammatory and immunological diseases.

The Role

Arda is seeking an experienced, self-driven scientist to lead in vitro pharmacology projects focused on developing the next-generation of immune-targeting therapies. This individual will play a pivotal role in developing and executing in vitro / ex vivo immunological assays to assess the efficacy of our therapeutic assets, with a particular emphasis on multispecific immune cell engagers. The ideal candidate will possess a strong background in cellular pharmacology, assay development, and large molecule d","datePosted":"2026-11-05","employmentType":"FULL_TIME","hiringOrganization":{"@type":"Organization","name":"Arda Therapeutics","sameAs":"https://www.ardatx.com/"},"url":"https://jobs.ashbyhq.com/arda-therapeutics/118fd2f5-be01-48d0-98d5-634f4974c748","jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"San Carlos, CA"}}},{"@context":"https://schema.org","@type":"JobPosting","title":"Principal Scientist, Ex Vivo Pharmacology","description":"

About Arda

Traditional pharmaceuticals modulate individual proteins and signaling pathways, aiming to nudge tissues and organs back toward health. But cells - not proteins - are the functional units of diseased tissue, and their behavior is governed by redundant networks that single-target drugs struggle to change. Arda Therapeutics offers a groundbreaking alternative: we target cells, not pathways. By depleting the specific pathogenic cells that drive chronic diseases such as fibrosis and inflammation, we shut down the entire network of dysfunction at once, rather than blocking one of many redundant nodes.

What makes this possible now is an explosion of single-cell data. Arda's discovery engine integrates multi-modal single-cell, spatial, and genetic data to pinpoint pathogenic cell states and the surface markers that distinguish them from healthy cells with unprecedented precision. We then engineer targeted biologics that eliminate only the harmful cells, sparing healthy tissue and opening the door to greater efficacy and episodic treatment. Backed by leading life-science and technology investors - and built by a team that blends computational biology, drug development, and deep cell-depletion expertise - Arda is defining a new domain of medicine for inflammatory and immunological diseases.

The Role

Arda is seeking an experienced, resourceful scientist to lead our Ex Vivo Pharmacology team. This individual will play a pivotal role in developing and executing ex vivo models to assess the efficacy of our therapeutic assets, with a particular emphasis on multispecific immune cell engagers. The ideal candidate will possess a strong background in ex vivo modeling, particularly precision cut tissue slice models, coupled with a proven track record of leading functional teams and managing ","datePosted":"2026-10-06","employmentType":"FULL_TIME","hiringOrganization":{"@type":"Organization","name":"Arda Therapeutics","sameAs":"https://www.ardatx.com/"},"url":"https://jobs.ashbyhq.com/arda-therapeutics/810f59e7-8068-467e-a622-c52313d9da8a","jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Arda headquarters"}}}]

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